Life What’s the hottest pepper in the world? It’s over 300 times spicier than a jalapeño. August 3, 2022March 30, 2023 Clare Mulroy, USA TODAY Comments Off on What’s the hottest pepper in the world? It’s over 300 times spicier than a jalapeño. The hottest pepper in the world is over 300 times spicier than a jalapeño, but that doesn't stop people from eating it — someone once ate 122 of them.