News Christina Applegate is ‘pretty convinced’ ‘Dead to Me’ will be her last acting gig amid MS November 13, 2022 Naledi Ushe, USA TODAY Comments Off on Christina Applegate is ‘pretty convinced’ ‘Dead to Me’ will be her last acting gig amid MS Christina Applegate filmed the third and final season of "Dead to Me" amid her diagnosis with multiple sclerosis. It may be her last role, she says.